I'm a Physics graduate student at Rice University with specialisation in biophysics.
In my research at Clementi's Group I'm utilizing computer simulations and tools from statistical physics to determine proteins behavior.
Proteins are significant both from theoretical and practical point of view. On one side, proteins are involved in most biological processes, such as enzymatic catalysis, photosynthesis and diseases. A fast and cheap method to determine how proteins behave would help in many applications. The current experimental methods are both slow and expensive. Unfortunately have trouble to determine properties of proteins.
From theoretical point of view, proteins are a challenge too. Proteins can have too many different possible shapes. This doesn't allow to predict the behavior of protein in a simple way. Only recently have powerful computers like Anton allowed to fold small proteins by brute force approach (Fig. 1). Brute force means that the protein is simulated exactly as it is in real world. The achieve reasonable accuracy it takes months or years to simulate miliseconds of protein behavior. Most protein don't fold in this short time. Only for fast-folding proteins the whole protein behavior can be simulated. This allowed to improve our understanding how proteins behave. Still, protein which fold on long timescales are out of reach.
email: eugen.hruska at rice edu
Anderson Biological Lab 319
Houston, TX 77005